Our ‘Young Chemist Award’ – This competition helps young PhD chemists reach out to a wider industrial audience and gain recognition for their work. It can also help boost confidence as each finalist gets to present their work in a short presentation. Being selected as a finalist and getting the opportunity to present is in

  CIA Awards Dinner Royal Armouries Museum, Leeds, 16th June https://www.cia.org.uk/ciaawards/Awards Our Events Director Hannah May enjoyed a fantastic evening at the CIA Awards Dinner in Leeds last week. Hannah was delighted to meet so many young chemists and felt truly invigorated and inspired by their enthusiasm for their work. She said that she wanted

I can’t begin to count the number of aryl boronic acids I’ve made and/or worked with over the years. These versatile intermediates will forever be part of the synthetic organic chemist’s toolbox. You would be hard pushed to find an organic chemist that hasn’t run a Suzuki- Miyaura cross coupling reaction at some stage in

Last weekend, I attended a celebration party for my PhD supervisor Professor Nicholas J. Turner on the occasion of him being elected as a Fellow of the Royal Society. This is a prestigious accolade only bestowed upon a few very worthy scientists including 85 Nobel laureates. Nick was elected as FRS in 2020 but due

We are very pleased to introduce Dr Jen Crawford from GSK.  Jen will be talking about ‘Implementing Statistical Modelling Tools into Early Phase Process Development Workflows’ at our ‘Organic Process Research and Development Conference’ in New Orleans on 22-24 June. This presentation will describe high throughput experiments (HTE) which provide an opportunity to traverse large

The count down has begun and we only have one month to go now until we come to New Orleans for our ‘47th Organic Process R&D Conference’ on 22-24 June. We are so excited about holding this face to face event in such a vibrant brilliant location!  The 3 day meeting will include 16 presentations

Scientific Update to Welcome New Technical Associate for North America & Asia Pacific – Dr Ben Littler Scientific Update is delighted to announce the appointment of Dr Ben Littler, formerly Executive Director  Process Chemistry for Vertex Pharmaceuticals. Ben will join the team at Scientific Update in August 2022 as Technical Associate, North America & Asia

Phenols and anilines are two of the most important building blocks in industrial chemical manufacturing. Any process capable of converting one into the other is going to generate a lot of interest, and a paper by Shi and co-workers does just that.1 Direct conversion of an aniline to a phenol is a relatively straightforward transformation

Process chemists at Genentech recently published their work on development of a kilo-scale synthesis of JAK-1 inhibitor- GDC-4379 (Figure 1).1The central heterocyclic core of the molecule consists of a 4-aminopyrazole moiety (elaborated as the pyrazolopyrimidene amide- presumably the inhibitor hinge binding fragment in the kinase active site) with an additional aryl substituent at C-3 and

Oxidation of allylic alcohols to enones, although on paper a simple reaction, usually requires insidiously toxic metals or metalloids such as chromium and selenium or hazardous peroxy- reagents.1 Scale-up of these methods remains particularly challenging. A team from GSK found themselves in precisely this position when developing a synthetic route to a steroid-derived HIV maturation