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Forthcoming
Conferences
29 October 2018 -
31 October 2018
Organic Process Research and Development
Meliá Milano, Italy
Book Now View Details Brochure11 December 2018 -
13 December 2018
5th Winter Process Chemistry Conference & Exhibition
Manchester
Book Now View Details Brochure27 January 2019 -
31 January 2019
14th Winter Conference on Medicinal & Bioorganic Chemistry
Steamboat Springs, Colorado
Book Now View DetailsForthcoming
Training
19 September 2018 -
20 September 2018
Practical Management of Impurities and Development of Effective and Comprehensive Control Strategies
Elite Palace Hotel, Stockholm
Fully Booked View Details Brochure19 September 2018 -
21 September 2018
Understanding Polymorphism & Crystallisation Issues in the Pharmaceutical Industry
Lisbon, Portugal
Book Now View Details Brochure24 September 2018 -
26 September 2018
Chemical Development & Scale-Up in the Fine Chemical & Pharmaceutical Industries
Prague, Czech Republic
Book Now View Details BrochureForthcoming
Webinars
Latest from The Lab Notes
Our Collection of Articles and News
A Kinetic Kick-Start: Deutetrabenazine (AustedoTM)- the First FDA Approved Deuterated Drug
A new paradigm in drug development began in the spring of last year with the Food and Drug Administration’s (FDA’s) approval of Teva pharmaceuticals’ VMAT2 inhibitor deutetrabenazine as a new chemical entity (NCE) under its 501(b)(2) legislation. This molecule is unique in that it is the first deuterium-substituted drug to reach the market and heralds
Oiling the cogs- Practical tips, useful facts and resources: Organometallic highlight:
The generation of lithium-alkoxide based aryl and heteroaryl Grignard reagents by Mg-Br/Cl exchange in toluene- increased reactivity and wide applicability. Organomagnesium-based organometallics are used extensively in organic chemistry.[1] Historically the reagents were prepared by direct insertion of magnesium metal into organic halides. With demand for more industrially applicable methods, halogen-magnesium exchange using alkyl magnesium halides
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