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Forthcoming
Conferences
11 June 2020 -
10 June 2021
Empowering Women in Organic Chemistry – Europe
AstraZeneca, Macclesfield
Book Now View Details09 December 2020 -
11 December 2020
Organic Process Research and Development
Basel, Switzerland
Book Now View Details08 March 2021 -
10 March 2021
Organic Process Research and Development
New Orleans, USA
Book Now View DetailsForthcoming
Training
26 May 2020 -
27 May 2020
VIRTUAL TRAINING EVENT | Drug Discovery Safety Assessment for Chemists
On-Line Event
Book Now View Details01 June 2020 -
05 June 2020
VIRTUAL TRAINING EVENT – Design, Development and Scale-Up of Safe Chemical Processes and Operations
On-Line Event
Book Now View Details Brochure02 June 2020 -
03 June 2020
VIRTUAL TRAINING EVENT | Drug Metabolism and Pharmacokinetics (DMPK) in Drug Discovery
On-Line Event
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Webinars
Latest from The Lab Notes
Our Collection of Articles and News
Breaking up is hard to do
As synthetic chemists we are very familiar with making chemical bonds, particularly C-C bonds, and building complex molecules. Having said that, fundamentally, with sufficient energy and entropy in the driving seat, it should be quicker and easier to break molecules apart. Deconstructive processes are not, however, as common as one might think- particularly cleavage of
A couple of interesting papers from Angewandte Chemie
1. Using an approved drug as a diazomethane surrogate1 A recent paper published in Angewandte Chemie describes the use of Temozolomide (TMZ) as a solid weighable diazomethane surrogate. TMZ is an approved drug and is the standout treatment for gliobastoma. It is stable weighable solid, with reasonable water solubility. Under physiological conditions , pH 7.4,
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