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Training
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Forthcoming
Conferences
11 December 2018 -
13 December 2018
5th Winter Process Chemistry Conference & Exhibition
Manchester
Book Now View Details Brochure27 January 2019 -
31 January 2019
14th Winter Conference on Medicinal & Bioorganic Chemistry
Steamboat Springs, Colorado
Book Now View Details08 April 2019 -
09 April 2019
Flow Chemistry and Continuous Processing Conference
Royal Sonesta Hotel, Boston
Book Now View Details BrochureForthcoming
Training
07 February 2019 -
08 February 2019
Practical Crystallization & Polymorphism
Mumbai
Book Now View Details Brochure11 February 2019 -
13 February 2019
Chemical Development & Scale-Up in the Fine Chemical & Pharmaceutical Industries
Mumbai
Book Now View Details Brochure28 February 2019 -
01 March 2019
Practical Crystallization & Polymorphism
Hyatt Place, Nashville
Book Now View Details BrochureForthcoming
Webinars
Latest from The Lab Notes
Our Collection of Articles and News
Enjoy the gin but spare a little thought for the tonic….
Gin is rapidly becoming the nations favourite tipple. Its undergone a modern renaissance with familiar trade names such as Gordon’s, Plymouth and London and multiple artisan distilleries appearing country-wide. It’s even drawn synthetic organic chemists out of the lab and into the refineries. This week at our 5th Winter Process Chemistry Conference in Manchester UK
Transition metal catalysis in vivo-cisplatin-mediated tertiary amide prodrug activation of cytotoxic agents in cancer cells
Figure: 1 The idea of using transition metal chemistry in a cellular setting might at first seem counterintuitive- biological conditions are challenging with respect to stability, efficiency and catalyst (not to mention patient) poisoning. Having said that many important intracellular processes are modulated by transition metals complexed in metalloproteins, with functions including storage and transport
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