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NEW Electronic Course Brochure

With many of our events going ONLINE, we have invested in some new software to allow us to share all our course manuals electronically in an e-Reader format. You can view how this works below by clicking on our NEW Electronic Course Brochure:

Call For Papers 2021

Do you have a topic that you would like to share with our international audience of organic chemists? We are currently inviting speakers to present technical papers at our events this year.   Flow Chemistry & Continuous Processing Conference – ONLINE – 10-11 May Catalysis in the Fine Chemicals Industries Conference – ONLINE – 2-3

Vaska’s complex- Reagent of the month

Iridium is ubiquitous in organic synthesis. In the last decade alone we have seen its impact as a phtoredox catalyst for a wide range of light-driven reactions that are difficult to achieve using traditional synthetic methods.1 In addition, iridium has rich utility in C-H activation chemistry- a recent review by Cramer highlighting chiral complexes as

Scientific Update – changing with the times during covid-19

As businesses around the world have had to postpone and cancel live meetings, conferences and training courses in response to COVID-19 disease, workplace and group training has become one of the earliest and hardest-hit business activities. We have found that 100% of companies we work with across the globe, have had to postpone or cancel their

Iridium catalysed C-H borylation of alkyl C-H bonds

Two recent papers in Science have described Iridium catalysed C-H borylation of alkyl C-H bonds. The first paper1 reports a C-H borylation of primary C-H bonds.  Initial experiments showed that dibutyl ether (used as substrate and solvent) could be converted to BuO(CH2)4Bpin and similarly THF could be borylated in the 3-position with 2-methylphenanthroline (2-mphen) as

Designing Crystallisation Processes

Three recent papers from the groups of Nagy and Qu have discussed different options for designing and scaling up crystallisation processes to achieve polymorph control and obtain the correct particle size distribution (PSD). The first two papers1,2 describe using PAT (online analysis) with feedback control to design an antisolvent crystallisation process for indomethacin.  Each paper

Call for Papers | Celebrating Women in Process Chemistry

In an effort to support and highlight the outstanding contributions of Women in Process Chemistry, the journal Organic Process Research & Development has decided to publish a Special Issue that will aim to highlight a select collection of papers from Women in the field of Process Chemistry. As a co-editor for this Special Topic Issue,

In full flow-continuously battling bacteria with boron

Increasing multidrug resistance to antimicrobial agents, particularly in Gram-negative bacteria, is a significant global healthcare challenge. Carbapenem-resistant enterobacteriaceae (CRE) has been declared as one of the most urgent drug-resistant threats in the United States. Much like the cephalosporin B-lactams in the 1980’s, heavy clinical reliance on carbapenem b-lactam antibiotics over the past few decades has

Breaking up is hard to do

As synthetic chemists we are very familiar with making chemical bonds, particularly C-C bonds, and building complex molecules. Having said that, fundamentally, with sufficient energy and entropy in the driving seat, it should be quicker and easier to break molecules apart. Deconstructive processes are not, however, as common as one might think- particularly cleavage of

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