52nd Organic Process Research and Development Conference

23 September 2024 - 25 September 2024
Grandior Hotel | Prague, Czechia
Spaces available

Event overview

We are so delighted to bring our 52nd OPRD Conference to Prague, Czech Republic 

Join us in this fantastic location and you will enjoy hearing cutting edge Scientific Content alongside our renowned Networking Receptions.  You will have the chance to connect with other like-minded chemists and benefit from Questions & Answer sessions and scientific discussion after each presentation.

Whether you are looking to learn about the latest scientific updates from industry or to meet and network with other chemists – our OPR&D Conference is the place to be.

Take advantage of our global network and extensive reach.

We invite key industrial experts from around the globe to share their discoveries with you. Each speaker is hand-picked and we work hard to ensure that a wide variety of topics are covered to ensure our programme is comprehensive and relevant. You will be re-invigorated and boosted once back in the lab.

Come and improve your efficiency and learn how to be more innovative in your synthetic route design, development and optimisation.

The chemical and pharma industries are fast moving and ever changing and the efficient conversion of a chemical process into a process for manufacture on tonnage scale has always been of importance. However, in the current economic and regulatory climate, it has become increasingly vital and challenging to do so efficiently and sustainably. OPR&D focusses on all these essential aspects of the chemical industry and has a reputation for quality and excellence.

We provide a safe, comfortable environment where you can meet new partners face-to-face, network with peers, and source innovative solutions in our exhibition area.

Please contact us if you are interested in Exhibiting or Sponsoring this event:  [email protected]

OPRD 2023 Barcelona

                 

Benefits of attending

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  • Continuing Professional Development (CPD ) keeps you up to date on current and emerging developments.
  • Learn from a wide range of industrial case studies given by hand-picked industrial speakers.
  • Take home relevant ideas and information that are directly applicable to your own work
  • Save time. Our intensive, commercial-free programme means less time away from work.
  • Network with the key people in the industry during the networking events

Who should attend?

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  • Process Research & Development Chemists
  • Chemical Engineers in Industry
  • Heads of Departments & Team Leaders

Sponsorship Opportunities

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We have several sponsorship opportunities still available for this conference. These include networking and reception sponsorship.

Your company logo with link to your website would appear here and for premium sponsorship such as networking and reception, adjacent to the conference pages as well.

If you are interested in sponsoring this conference, please contact Dr Claire Francis: [email protected] 

MEDIA SPONSORS

 

Event speakers

Dr Simon Wagschal
Dr Simon Wagschal
Lonza, Switzerland
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Simon Wagschal currently works within Lonza’s Advanced Chemistry Technologies team.
Prior to this, he worked within Janssen External R&D team, focusing on compounds in early development and delivering GxP batches at CRO partners.
Simon also worked in Janssen’s Chemical Process R&D group and was involved in a dozen late-stage projects, developing and introducing new processes in the pilot and production plants.
He received the Vice Presidents’ Research Award for Outstanding Technical Achievement in 2020.

 

Simon earned his Ph.D. in 2010 from École Polytechnique, Paris, France, under the supervision of Prof. El Kaïm and Prof. Grimaud.
He then delved into organometallic chemistry during his postdoctoral stay with the Kündig group in Geneva, Switzerland.

 

Dr Roland Götz
Dr Roland Götz
BASF, Germany,
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1968:                  Born in Rothenburg, Germany

1993:                  Diploma degree in chemistry at university Würzburg

1996:                  Dissertation at university Würzburg at Prof. Bringmann
incl.
research exchange to US (National Cancer Institute, Maryland)
Total Syntheses of anti-HIV active Michellamines and related analogs
Summa cum laude as well as awarded by the “curatorship of Franconian memorial foundation” due to TOP-dissertation of whole university.
Scholarship by “Fonds of chemical industry”.

1996:                  Start industrial career at BASF
Research Scientist within Crop Protection Research

1999-2001:        Assistant Plant Manager (Multi-Purpose Plant Fine Chemicals)

2001-2003:        Plant Manager (Multi Purpose Plant Plant Fine Chemicals)

2003-2006:        Technology Manager
Technological responsibility for several active ingredients at different production locations with respect to process & synthesis optimization, yield increase, waste reduction, reduction of Cost of Goods, Capacity increase

2006-2011:        Head of Global Responsible Care within Global Operations
Ensurance of safe operations as well as quality for active ingredients as well as formulated products

2012-today:      Leading department Chemical- and Process Development within
Crop Protection Research at BASF
Development of new production processes for new active ingredients with focus on safe, robust and sustainable processes by minimum costs

2016:                  Awarded as “Senior Executive Expert Process Development” within BASF
Official announcement within BASF Group: “Over the past 20 years, Roland has held positions in R&D, technology and manufacturing, supporting several key projects during development and production. During his tenure with BASF, Roland has gained broad expertise in process development and operations, and he is recognized as an expert within BASF, in the industry and in academia”

2014-2017:        Teaching assignment at Johannes Gutenberg-University Mainz
Teaching and examining of bachelor students. Subject on Technical Chemistry with focus on Process Development within study course “Applied organic chemistry”

2017-2021:        Lecturer at Johannes Gutenberg-University Mainz
Reading “Industrial process technology with focus chemical process development”

2022/2023:        Lecture as Guest Instructor at the IIT Bombay within “Techno-commercial Aspects within Fine Chemicals”

 

Patents / Publications (only industrial career, without activities at university)

Holding more than 250 patents or applications respectively globally.
Prof. Hashmi et al., Roland Goetz – Adv. Synth. Catal. 2023, 365, 11, 1794-1800
Prof. Hartwig et al., Roland Goetz – Angew. Chem. Int. Ed. 2021, 60, 399
Prof. Reisman et al., Roland Goetz – Org. Lett. 2022, 24, 21, 3802–3806
Prof. Hashmi et al., Roland Goetz, Green Chemistry 2021, 23, 8169-8180
Prof. Kappe et al., Roland Goetz – Org. Process Res. Dev. 2017, 21, 1, 125
PS: Further publications during PhD-work not considered here

 

Invitation to expert conferences and holding lectures

2023 Shanghai (The XXIII International Conference on Organic Synthesis): “Fenmezoditiaz – Synthesis & Process Development of a structurally complex, chiral, mesoionic Insecticide”

2022 Indian Institute of Technology Bombay: “Sustainability in Process Chemistry”

2022 Basel (Organic Process Research and Development): “Sustainability in Process Chemistry”

2017 University of Münster (FoChin): “Crop Protection Research & Process Development”

2016 Prague (Organic Process Research and Development): “Challenges and Solutions within Process Development of a Large Scale New Fungicide”

2015 Indian Institute of Technology Bombay: “Industrial Process Development at BASF Crop Protection“

2015 Pune (Organic Process Research and Development): “Process Development within Crop Protection”

2015 Shanghai Institute of Organic Chemistry: „Crop Protection Research at BASF with focus on Process Development“

2014 Brussels (Organic Process Research and Development): “Process Development of Active Ingredients for Crop Protection“

Dr Samantha Staniland
Dr Samantha Staniland
AstraZeneca, UK
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Sam graduated from The University of Manchester, UK, in 2011 with an MChem in Chemistry with Industrial Experience, while carrying out her industrial placement at Pfizer, UK, in Medicinal Chemistry. In 2011–2015, Sam completed a PhD in the groups of Professor Jonathan Clayden and Professor Nicholas Turner on the ‘Biocatalytic Asymmetric Synthesis of Atropisomers’. Sam joined Johnson Matthey in 2015 where she developed expertise in Biocatalysis and Homogeneous Catalysis. In 2021, Sam was hired by AstraZeneca, bringing her expert knowledge of Biocatalysis to their Process Chemistry Depeartment. Since 2022 Sam has been leading the expansion of AstraZeneca’s High-Throughout Experimentaion capabilties in the new Discovery Centre in Cambridge.

Dr Stephanie Kosnik
Dr Stephanie Kosnik
Boehringer Ingelheim, Germany
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Stephanie is currently on an ex-pat assignment as a Principal Scientist in the Crystallization Lab at Boehringer Ingelheim in Biberach, Germany.

Stephanie received her Ph.D. in Chemistry from the University of Windsor, Ontario, Canada with Prof. Charles L.B. Macdonald in 2017. There, she specialized in Crystallography and organophosphorus transformations. After working at several different chemical companies in the polymer industry, she joined Boehringer Ingelheim as a Senior Scientist in the Solid-State Science & API Engineering lab in Ridgefield, CT in April 2021.

Dr Dide Verhoeven
Dr Dide Verhoeven
Symeres, Netherlands
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Dr. ing. Dide Verhoeven is a Chemical Project Leader in process research and development at Symeres Weert, in the Netherlands. Her focus is on the development of safe and efficient processes for kg-scale manufacture of complex small molecules and APIs. Dide started in the company as a PR&D chemist in 2020.

 

Prior to her work in industry, Dide received her MSc degree in chemistry and physics from Utrecht University in 2014, with a focus on organometallics and biochemistry. She obtained her doctoral degree in 2018 in the group of Dr. Marc-Etienne Moret at Utrecht University, with a specialization in organic synthesis and homogeneous catalysis. After this, she moved to Switzerland for postdoctoral research in the group of Prof. Martin Albrecht, investigating the use of Fe-based catalysts for oxidative transformations. With her experience in homogeneous catalysis, Dide brings unique expertise to her current role at Symeres, thereby advancing the company’s capabilities in metal catalyzed reactions at large scale.

 

Dr Shio Komiya
Dr Shio Komiya
Chugai Pharmaceutical Co., Ltd, Japan
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Shio Komiya received BS from Massachusetts College of Pharmacy and Health Sciences in 2004 under the direction of Professor Charles Kelley. He received MS from Boston College in 2007 under the direction of Professor Scott Miller, after studying enantioselective and site-selective organocatalytic reactions. He began his professional career as a process chemist at Takasago International Corporation in 2008, where his role was centered on the development of ruthenium-catalyzed enantioselective hydrogenation reactions encompassing laboratory, pilot, and plant scales. He joined Chugai Pharmaceutical in 2013 and has worked on the process development of various small to mid-sized molecule APIs including peptide drugs. In his current position as Manufacturing Technology Development Professional for Mid-Sized Molecule APIs, he plays a leading role in the development of enabling technologies for the efficient synthesis of complex APIs.

Dr Carl Reens
Dr Carl Reens
AstraZeneca, UK
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Principal Scientist (Manufacturability and improvement) at AstraZeneca working on the commercial portfolio of Active Pharmaceutical Ingredients within Global Chemical Development at AstraZeneca, Macclesfield UK

Qualified chemist with 30 years’ Industrial Pharmaceutical experience in Process Development and scale-up within process chemistry for development projects, pilot plant manufacture for clinical supply and technical stewardship of commercial and established products. I am self-motivated, energetic, a strong scientific leader and I enjoy working as part of multidisciplinary teams with a breadth and depth of technical knowledge, driving novel solutions and bringing innovation to projects. I am expert in technology transfer and able to succeed in producing API’s and intermediates within stringent deadlines. Started as a process chemist with Fison’s Pharmaceuticals, Chemical Development back in 1994, seems like only yesterday! Love the challenges on projects and working with other people across the Globe with experiences at Dow Chemicals (Stade Germany), Rhone-Polenc Rorer (Paris, France) and Astra AB (Sodertalje, Sweden)

Dr João Sardinha
Dr João Sardinha
Hovione, Portugal
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João received his Ph.D. in Organic Chemistry in 2009, specializing in carbohydrates, from both the University of Lisbon and Université Pierre et Marie Curie – Paris VI, under the supervision of Prof. Amélia P. Rauter and Prof. Pierre Sinaÿ. Following his Ph.D., he conducted postdoctoral research in molecular dynamics simulations at NOVA School of Science and Technology in Lisbon, focusing on CO2 solubility in ionic liquids and protein-ligand interactions.

In 2013, João joined Hovione as an Assistant Chemist in the Process Chemistry Development department. Throughout his career, he has been involved in developing and optimizing various processes, as well as their introduction to pilot plant and manufacturing areas. More recently, he has participated in digitalization projects and Hovione’s internal R&D programs aimed at enhancing sustainability. Currently, he is a Senior Scientist at Hovione.

Dr Larry Wang
Dr Larry Wang
Pharmablock, China
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About me: I am based in Nanjing, China, leading the Tech Innovation Center (TIC) of PharmaBlock group. I got my PhD from U of Minnesota in 2018, and BS from Peking University in 2013. Author of over 10 publications and patents. Formal name is Yuanxian Wang, I can go by Larry Y. Wang.

About PharmaBlock: we are a small-molecule CDMO company operated in China and the US, focusing on innovating chemistry and low-carbon technologies, for a greener and healthier world. We strive to contribute to the sustainable development of the industry.

About the Tech. Innovation Center: The disciplines we work on are continuous production including continuous hydrogenation, homogeneous and heterogeneous catalysis, biocatalysis, innovative waste treatment, process safety, and data-driven R&D We look forward to applying these technologies in production of API’s, intermediates, and RSM’s. it is the work from this center that won the ACS CMO Excellence in Green Chemistry Award two years in a row.

Dr Stephen Wainwright
Dr Stephen Wainwright
Johnson Matthey, UK
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Steve studied at the University of York, UK, completing his MChem degree in 2006 and MSc in Liquid Crystals and Nanoscience in 2007. This was followed by an EPSRC funded PhD in heterogeneous PGM catalysts, completed in 2012 at the University of York. He then joined Syngenta as a Physical Chemist for 2 years researching co-crystals of APIs.

 

In 2014, Steve joined Johnson Matthey as a Development Chemist, focusing on developing new industrial heterogeneous PGM catalysts for petrochemical and bio-renewable applications from inception, through scale-up and manufacture.

 

In his current role as Product Specialist, Steve is responsible for a portfolio of heterogeneous catalysts, supporting the development and manufacture of new and existing catalysts within the business.

Dr Mark Ford
Dr Mark Ford
Bayer, Germany
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Vita

2021 –                  Distinguished Science Fellow, Bayer AG, Crop Science Division

2011 – 2022       Head of Process Research, Bayer AG, Crop Science Division

2002 – 2011       Group Leader, Process Research Frankfurt, Bayer AG, Crop Science Division

2000 – 2002       Group Leader, Process Research Frankfurt, Aventis CropScience

1993 – 2000       Team Leader, Process R&D, AgrEvo, Frankfurt

1990 – 1993       Biochemical Synthesis / Herbicide Research, Schering Agrochemicals, Cambridge

1988 – 1990       NATO Post-Doctoral Fellow, Prof. S.V.Ley, Imperial College, London

1985 – 1988       PhD., Dr. R.T.Brown, University of Manchester

 

Expertise/Interests:

Biocatalysis and biocatalyst / strain optimization

Agrochemical process research

(Multi-nuclear) metal catalysis
AI and QM supported reaction optimization / modelling

 

Dr Kiran Matcha
Dr Kiran Matcha
Johnson & Johnson, Belgium
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Kiran received in 2011 his PhD degree in organic synthesis from Indian Association for Cultivation of Science, Kolkata, India. He moved to Europe for post-doctoral research, first at the University of Groningen, The Netherlands (2011-2012) followed by Max-Planck Institute of Molecular Physiology, Germany (2012-2014).

In 2014, he started his industrial career joining the Chemical Process Research and Development (CPRD) organization at Johnson&Johnson Innovative Medicine, Beerse, Belgium. As a process chemist, he developed cost-effective and robust chemical process for small molecule APIs spanning from early clinical phase supplies to commercial manufacturing routes. He led research projects with internal, external resources (CROs and CDMOs) and participated in CMC meetings.

In 2019, he moved to a newly formed Discovery Process Research (DPR) group within the same organization, as a founding member. In his current role, as a DPR lead, support several discovery programs from SAR enabling chemistry identification to developing efficient synthesis routes to deliver pre-clinical API batches. He is also part of the decisional core team responsible for program strategy and execution towards drug discovery stage gates.

In his career, he gained knowledge and experience in a broad-spectrum of drug discovery and development topics, across different therapeutic areas, including novel modalities.

Dr Gabriel Schäfer
Dr Gabriel Schäfer
Biosynth, Switzerland
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Dr. Gabriel Schäfer studied Chemistry at the University of Basel. He then moved to ETH Zürich to obtain his doctorate under the supervision of Prof. Jeffrey Bode, working on Friedel-Crafts benzylations and the synthesis of sterically hindered amides. After completing a postdoctoral research stay with Prof. F. Dean Toste at the University of California, Berkeley, he started his industrial career in 2015 as a Process Chemist at Actelion Pharmaceuticals in Allschwil (Switzerland). After the acquisition of Actelion by Johnson & Johnson and the subsequent demerger of Idorsia Pharmaceuticals in 2017, he worked as a Senior Scientist in Idorsia’s Chemistry Process R&D group. In this function, he developed scalable chemical processes for a wide range of preclinical candidates (incl. ACT-1004-1239, ACT-1014-6470 and IDOR-1117-2520, Phase 1/2) and new manufacturing routes for several late-stage or commercial products such as clazosentan (approved in Japan & South Korea), vamorolone (approved by FDA & EMA) and cenerimod (Phase 3). In 2020, he was promoted to Group Leader of the Chemistry Process R&D group, leading and overseeing 6 PR&D labs, a crystallization lab and the in-house Kilolab. After over 8 years at Actelion/Idorsia, Gabriel started a new position in 2024 as Director, Global Head of Chemistry at Biosynth, being responsible for the global R&D and production sites of the Complex Chemical division.

Gabriel is very passionate about spreading the art & science of Process Chemistry through publications and presentations. By now, he has co-authored over 30 publications and patents. He also serves as a member of the Early Career International Advisory Board of Helvetica Chimica Acta and the Advisory Board of Synthesis. in 2022, he was awarded an Industrial Junior Scientists Participation Fellowship Award for the prestigious Bürgenstock conference.

Dr Michael O'Keefe
Dr Michael O'Keefe
Gilead, USA
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Mike received his B.S. in Chemistry from the University of Wisconsin – Madison and his Ph.D. in Organic Chemistry from the University of Texas at Austin under the supervision of Prof. Stephen F. Martin. While in Austin, he developed a novel carbonylative cross-coupling methodology and completed the total synthesis of isokidamycin. Mike then moved to California where he was an American Cancer Society postdoctoral fellow in the labs of Prof. Barry Trost at Stanford. While there, he helped develop several metal-catalyzed reaction methodologies and another total synthesis. Mike then began his industrial career with Gilead Sciences where he is currently Director of Process Chemistry. In his current role, Mike leads Gilead’s efforts to implement Quality by Design concepts across the development timeline. Mike is also the process chemistry lead for obeldesivir, an investigational drug for the treatment of emerging viruses. Over the last 11 years at Gilead, he has also had the opportunity to work on numerous other development projects, including lenacapavir, which is the topic of his seminar today.

Sponsors

Interested in sponsoring an event?

If you are interested in Sponsoring this event we still have some great sponsorship opportunities available at the conference. See our sponsorship section on the advantages that sponsorship can bring to your business or contact Dr Claire Francis at [email protected]

Exhibitors

InCatT B.V.

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PharmaBlock

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Technobis Crystallization Systems

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Zaiput

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Zeon Corporation

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Why exhibit?

  • Meet delegates from key international companies
  • Interact directly with senior scientists, department heads and key decision-makers
  • Ability to demonstrate your company’s products or services

The conferences are designed to provide exhibitors with the maximum time to network with delegates.

Other Information

Benefits of Attending

arrow
  • Continuing Professional Development (CPD ) keeps you up to date on current and emerging developments.
  • Learn from a wide range of industrial case studies given by hand-picked industrial speakers.
  • Take home relevant ideas and information that are directly applicable to your own work, with the full proceedings in colour.
  • Save time. Our intensive, commercial-free programme means less time away from work.
  • Network with the key people in the industry via the networking receptions

General Information

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Registration for each conference includes:

  • Attendance at all the sessions
  • Access to a mobile events app connected to the conference
  • Lunch & refreshments daily
  • Unlimited access to the exhibition
  • Place at the networking reception

Why Exhibit?

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  • Meet delegates from key international companies
  • Interact directly with senior scientists, department heads and key decision-makers
  • Ability to demonstrate your company’s products or services

Sponsorship

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Promote your company at one of our prestigious conferences with sponsorship packages to suit your budget.

Please contact Dr Claire Francis

FREE POSTER BOARD

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Registered academic delegates can present a scientific technical poster FREE and have this published in the conference proceedings.

Please send an abstract of your poster via email.

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52nd Organic Process Research and Development Conference

23 September 2024 - 25 September 2024
Grandior Hotel | Prague, Czechia