Archived: VIRTUAL TRAINING EVENT | Design of Experiments for Chemists and Engineers
(DoE)
Date: 05 October - 08 October 2020
Location: Online Platform
Tutors: Dr Paul Murray
We are now delighted to offer this course ON LINE, the course will be delivered over 4 afternoon sessions as follows and timings are set in BST (British Summer Time):
Monday October 5th, 2020 | 1.30 – 5.30pm
Tuesday, October 6th, 2020 | 1.30 – 5.30pm
Wednesday, October 7th, 2020 | 1.30 – 5.30pm
Thursday, October 8th, 2020 | 1.30 – 5.30pm
The on line course price includes the option to book a one hour FREE consultancy slot with Dr Paul Murray to discuss any specific designs. This consultancy slot will be carried out off line and must be booked within 6 months of the course date. Bookings will be subject to Dr Murray’s availability and booked on a first come first served basis.
Industrial Scientists can no longer afford to experiment in a trial-and-error manner, changing one factor at a time. A far more effective method is to apply a systematic approach to experimentation that considers all factors simultaneously.
This approach is called Design of Experiments (DoE) and many scientists use it as an efficient way to solve serious problems afflicting their projects.
DoE provides information about the interaction of factors and the way the total system works, something not obtainable through traditional testing methods. DoE also shows how interconnected factors respond over a wide range of values, without requiring the testing of all possible values directly. DoE is a fundamental aspect of Quality by Design.
This now four session course written and presented by Dr Paul Murray a Process Chemist with extensive experience of applying DoE across a wide range of chemical reactions from reaction screening and new route development through to reaction optimisation.
The Course will empower Scientists to implement DoE in their work to more efficiently improve their processes.
Please do see brochure attached for more information (please note this is based on the live 2 day course, but the content is the same)

Course Outline
- Understand the DoE process.
- Select process factors and suitable ranges.
- Understand the different types of experimental design and when to use them.
- Identify main effects, interactions and interpret DoE models in relation to chemical understanding.
- Understand where DoE will solve a problem and when to consider complementary techniques like reaction progress kinetics to probe more challenging processes.
Session 1
- Introduction to the principals of Design of Experiments with a comparison with traditional methods.
- Introduction to DoE language and the DoE process. How to identify potentially important factors and ranges.
Session 2
- Designs for 2 factors.
- Taylor’s expansion and an introduction to the maths.
- Designs for 3 and more factors.
- Work Shop: Selecting factors and Ranges
Session 3
- Fractional Factorial designs. Different design types from screening designs to optimisation and robustness designs.
Session 4
- How and when to use the different design types. Workshop: Calculating main effects and identifying interactions
Session 5
- Principal component analysis (PCA) for solvent selection.
Session 6
- Workshop: implementing DoE.
Session 7
- Case studies.
Session 8
Review of the course and questions
Benefits of Attending
- Gain a comprehensive understanding of DoE
- Learn how to use DoE to efficiently scope out reaction space and optimise new reactions
- Link DoE with process development and quality by design
- Development of novel, effective and robust solutions
- Increased reaction understanding
- Apply DoE in case-studies
The on line course price includes the option to book a one hour FREE consultancy slot with Dr Paul Murray to discuss any specific designs. This consultancy slot will be carried out off line and must be booked within 6 months of the course date. Bookings will be subject to Dr Murray’s availability and booked on a first come first served basis.
Who Should Attend
- Lab scientists
- Process development scientists
- Industrial researchers
- Project managers
What's Included
The course fee includes:
- all four sections of the course
- course certificate at the end
You will have the option of buying a hard copy of the manual and this will be sent via the post to you. Please note for on line courses no PDF version of the slides/manual will be sent via email and no recordings are available after the event.
The on line course price includes the option to book a one hour FREE consultancy slot with Dr Paul Murray to discuss any specific designs. This consultancy slot will be carried out off line and must be booked within 6 months of the course date. Bookings will be subject to Dr Murray’s availability and booked on a first come first served basis.
Testimonials
Hovione Delegate
The course was very helpful to understand the DoE approach.
Société Suisse des Explosifs Delegate
Thank you very much to Paul and Laura! I have learned a lot about the theory and application of DoE, well-equilibrated course. I’ll definitely recommend it!