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In-House Training

Practical Catalysis

Tutors: Professor Chris Frost Professor Michael Willis Dr Will Watson

The Practical Catalysis course comprises lectures and problem sessions designed to illustrate how state-of-the-art catalytic methods can be applied to practical issues in small molecule synthesis. The content will focus on problems and targets relevant to pharmaceutical and agrochemical and fine chemical interests.

An emphasis will be placed on practical solutions. Topics covered will include: Pd and Cu catalysed C-C and C-X bond forming processes; Base metal catalysis; C-H activation for synthesis; Catalytic methods for fluorination; Photoredox catalysis; Rh catalysed conjugate additions; gold catalysis; catalysis in heterocycle modification and synthesis; emerging areas in catalysis.


Course Outline

  • Introduction to Practical Catalysis
  • Basic cross-coupling reactions
  • Pd and Cu catalysed C-Xbond forming processes
  • Catalytic C-C bond forming processes
  • Cyanation, Hydroformylation and Carbonylation
  • Gold catalyzed reactions
  • Borrowing Hydrogen and Hydrogen-mediated processes
  • Base metal catalysis
  • Catalytic C-H activation processes for organic synthesis
  • The catalytic synthesis and modification of heterocycles
  • Catalytic C-H activation processes for organic synthesis
  • Catalytic fluorination and trifluoromethylation chemistry
  • Photoredox catalysis
  • Case studies – Practical applications of catalysis in industry
  • Emerging areas in catalysis for organic synthesis
  • Problem sessions and synthesis challenge

Who Should Attend

Process Chemists wishing to maximise their knowledge and understanding of catalysis being applied in organic synthesis.
Medicinal Chemists wishing to keep their contemporary synthetic chemistry know-how at the cutting edge.
Production Chemists wishing to maintain their awareness of emerging catalytic chemical technologies.
Analytical Chemists who wish to gain a broader appreciation of organic chemistry .
Chemical Engineers wishing to maintain their awareness of emerging catalytic technologies.
Experienced Chemists looking to refresh and/or augment their knowledge of catalytic organic synthesis .
Students who are about to enter industry or post-graduate research and can obtain company sponsorship.
Young Chemists who have just started work in industry as organic chemists .
Managers who might benefit from an overview of the latest chemical technology available for use in the pharmaceutical, fine chemical and allied industries today.


What's Included

The course fee includes:

  • comprehensive course manual
  • coffee/tea refreshments breaks throughout each day
  • buffet lunch each day
  • course dinner on the first evening
  • course certificate
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