In-House Training
Practical Catalysis
Tutors: Professor Chris Frost Professor Michael Willis Dr Will Watson
The Practical Catalysis course comprises lectures and problem sessions designed to illustrate how state-of-the-art catalytic methods can be applied to practical issues in small molecule synthesis. The content will focus on problems and targets relevant to pharmaceutical and agrochemical and fine chemical interests.
An emphasis will be placed on practical solutions. Topics covered will include: Pd and Cu catalysed C-C and C-X bond forming processes; Base metal catalysis; C-H activation for synthesis; Catalytic methods for fluorination; Photoredox catalysis; Rh catalysed conjugate additions; gold catalysis; catalysis in heterocycle modification and synthesis; emerging areas in catalysis.
Course Outline
- Introduction to Practical Catalysis
- Basic cross-coupling reactions
- Pd and Cu catalysed C-Xbond forming processes
- Catalytic C-C bond forming processes
- Cyanation, Hydroformylation and Carbonylation
- Gold catalyzed reactions
- Borrowing Hydrogen and Hydrogen-mediated processes
- Base metal catalysis
- Catalytic C-H activation processes for organic synthesis
- The catalytic synthesis and modification of heterocycles
- Catalytic C-H activation processes for organic synthesis
- Catalytic fluorination and trifluoromethylation chemistry
- Photoredox catalysis
- Case studies – Practical applications of catalysis in industry
- Emerging areas in catalysis for organic synthesis
- Problem sessions and synthesis challenge
Who Should Attend
What's Included
The course fee includes:
- comprehensive course manual
- coffee/tea refreshments breaks throughout each day
- buffet lunch each day
- course dinner on the first evening
- course certificate
