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Photochemistry

Photochemistry has to me always seemed to be an area whose potential for industrial manufacture has never been realized. I may be biased (I did my PhD on photochemistry from 1967-1970) but I feel the tremendous synthetic potential of photoreactions has not been exploited enough.  One of the reasons is that scale up of batch

Particle Size Control in Batch Crystallisation of Pyrazinamide on Different Scales

In the past, the particle size of finished APIs was mostly controlled by processes such as milling and micronization, but this often creates fines and can lead to formulation issues for some compounds. More recently companies are trying to control the particle size of the product as part of the crystallisation process (not forgetting that

Iron Catalysis in Organic Synthesis – A Critical Assessment of What it Takes To Make This Base Metal a Multitasking Champion

Industrial homogeneous catalytic processes are dominated by the use of expensive precious metals and rely on very efficient catalytic cycles for their cost effectiveness. Many of the processes carried out with precious metals are also achieved by iron catalysis, but often other processes compete and these chemistries have not been so widely used in industry,

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