VIRTUAL TRAINING EVENT | Safety & Selectivity in the Scale-Up of Chemical Reactions

Date: 05 November - 10 November 2020

Location: On-Line Event

Tutors: Dr Will Watson, Dr John Studley

We are delighted to be able to offer this course now ON LINE, this two day course will be divided up into four sessions using a online platform, dates and times are as follows and set in GMT (Greenwich Mean Time):

Thursday, November 5th | 2.00pm – 5.00pm GMT
Friday, November 6th | 2.00pm – 5.00pm GMT
Monday, November 9th | 2.00pm – 5.00pm GMT
Tuesday, November 10th | 2.00pm – 5.00pm GMT

The safety of chemical processes is critical for the whole chemical industry. It is vital that process development chemists and engineers are able to identify aspects of the chemistry that may be hazardous or pose a risk to the safety of the process or equipment.

In order to do this they need to know when to proactively engage colleagues or contractors to carry out process safety testing and hazard analysis, which in turn requires a knowledge of the equipment and test methods available.

As chemical reactions are scaled up and operations become more economic the ability to remove heat from exothermic events becomes reduced and at the same time the outcome of any incident becomes much more severe.

This is an almost unique course on the safety of chemical reactions and processes that is designed by chemists for chemists (and engineers) with the ultimate aim of helping the chemical industry reduce the number of chemical or process related incidents.

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Course Outline

The aim of the course is to give lab chemists an understanding of the issues that need to be considered during the early stages of scale up to large laboratory scale equipment (10-20 litre vessels) / kilo lab. The course will concentrate on chemical safety and selectivity issues and include information on what safety testing equipment is available and the uses and limitations of this equipment. Attendees will learn how to identify potential problems whether they be thermal hazards or selectivity issues. Methods used by other companies for handling hazardous reagents and reactions will be described as well as alternative chemistry to circumvent these reactions and/or reagents.

Benefits of Attending

  • Attendees will learn how to identify potentially unsafe chemical processes, particularly those that pose more a danger on scale
  • They will learn about what testing procedures are available to help them identify unsafe operating conditions to enable to talk knowledgably to in-house safety professionals or contract organizations
  • Sources of safety information in the literature and via the internet will be provided
  • The course provides lists of reagents and functional groups that should trigger safety testing studies
  • Methods used in other companies for handling hazardous reagents and reactions will be provided
  • Alternatives reagents or substitutes for hazardous materials will also be discussed
  • Recommendations will be provided for making the first sample of a product where there may be safety or stability concern


Who Should Attend

Any laboratory chemist involved in the scale-up to large scale equipment/kilo lab

What's Included

The course fee includes:

  • all six sections of the course
  • course certificate at the end

You will have the option of buying a hard copy of the manual and this will be sent via the post to you.  Please note for on line courses no PDF version of the slides/manual will be sent via email and no recordings are available after the event.   Please note recordings of any sessions will not be shared.


Solvay Fluor GmbH

Good talks from Will, good slides. All in all a very useful course!


SI Group

Professional teacher for this course adds understanding  to important parameters to follow (even if it is not the same chemistry). Thank you for this course!