Date: 21 April - 22 April 2020

Location: On-Line Event

Tutors: Dr Will Watson

This is a VIRTUAL short course that will look at synthetic and scale up aspects of making and using Grignard reagents.  The course will be in two sections of 60-90 minutes held over two consecutive days as follow:

APRIL 21st, 2.30 – 4.00 pm (UK)  |  Session 1:  Making Grignard reagents and safety aspects of making and handling Grignard reagents.

This presentation will cover the main ways for preparing organomagnesium compounds, and consider their relative reactivity and stability once prepared.  In addition the safety issues associated with making organomagnesium compounds will be discussed.  The presentation will use real life case studies to illustrate the various aspects of preparation, stability and safety.

  • Introduction
  • Making Grignard reagents on scale
  • Safety issues

APRIL 22nd , 2.30 – 4.00 (UK) |  Session 2:  Recent examples of using Grignard reagents, and making Grignard reagents in continuous flow mode.

This presentation will cover recent developments in the use of Grignard reagents such as Kumada and Negishi couplings along with the preparation and use of Grignard reagents in flow with particular emphasis on the scale up of flow processes for the preparation of Grignard reagents via industrial case studies.

  • Recent examples of using Grignard reagents
  • Making Grignard reagents in continuous flow mode.

This online course will be of interest to anyone involved in synthetic organic chemistry, since every chemist will run at least one Grignard reaction in their life.

When you register you will be sent links to join the on-line sessions. These will take place at the following time each day:

2.30 – 4.00 pm  |  UK

3.30 – 5.00  |  Central Europe

09.30 – 11.00 |  Eastern US

6.30 – 8.00 am  |  West Coast US

As space is limited there is a small charge of £95.00 + VAT* per person (*only if based in the UK, other countries will be out of scope) Payments only available via credit card.

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