VIRTUAL TRAINING EVENT | C-N Cross Coupling

This is a VIRTUAL short course this short course will focus on the C-N -aryl-and -heteroaryl cross-coupling approaches outlined below, including examples and case studies from the pharmaceutical and agrochemical industries.

June 29, 1.30 – 4.30 pm (UK)  |  Session 1

June 30, 1.30 – 4.30 (UK) |  Session 2

Since the pioneering work of Migita and co-workers in 1983, the use of palladium for C(sp2)-N bond formation has become one of the most important reactions in industrial organic chemistry.  Process improvements, catalyst/ligand refinements and deep mechanistic understanding has led to the establishment of what nowadays is known as the Buchwald–Hartwig amination reaction. Synthesis of both pharmaceutical and agrochemical active components rely heavily on this methodology, embracing a wide range of structurally diverse substrates at all stages of development. In addition, use of base-metals such as nickel and copper offer complimentary approaches for making key C-N bonds in a wide range of substrates. Non-metal based approaches such as S_NAr chemistry and organocatalysis complete the gamut of methodology available to access this key synthetic transformation.

The content will be of interest to organic chemists- both in industry and academia- and anyone interested in finding out more about this important transformation.

When you register you will be sent links to join the on-line sessions. These will take place at the following time each day:

1.30 – 4.30 pm  |  UK

2.30 – 5.30  |  Central Europe

08.30 – 11.30 |  Eastern US

5.30 – 8.30 am  |  West Coast US

As space is limited there is a charge of £195.00 + VAT* per person (*only added if your company is based in the UK) Payments only available via credit card.