Event overview
Flow chemistry has been used in petrochemical and bulk chemical production for over 100 years, but has only seen significant interest in the pharmaceutical and fine chemical industries in the past 10 years. This course aims to give an introduction to this exciting and revolutionary field, to familiarise attendees with the current state of the art.
A wide range of highlights from the flow chemistry literature will be discussed, from both academia and industry, with a focus on translating conventional reactions to flow processes. Attendees will become familiar with a number of distinct types of flow reactors, allowing the correct reactor to be chosen to suit the required chemistry. Emphasis will also be placed on the inline and online monitoring of flow reactions, along with the hazards and pitfalls associated with scaling up flow reactions.
Meet the Experts at CCFLOW / Final Q&A session on Thursday
Don’t miss a Q&A Session with members of the CCFLOW Lab with a focus on technical/equipment issues
This course will be held across four live sessions. Dates and timings are as follows:
PST: 6.00am-9.00am | CST: 8.00am-11.00am | EST: 9.00am-12.00pm | GMT: 2.00pm-5.00pm | CET: 3.00pm-6.00pm
– Monday, November 9th
– Tuesday, November 10th
– Wednesday, November 11th
– Thursday, November 12th
Course Outline
Session 1:
Introduction to Flow Chemistry and Continuous Processing
Current status of flow chemistry and continuous processing (industry)
Why flow – current drivers for flow chemistry and continuous processing
Literature survey and general flow chemistry principles
Basics of heat and mass transfer / reaction engineering
Equipment survey / flow chemistry at CCFLOW
Flash Chemistry
Strongly exothermic and/or mixing sensitive/fast reactions (i.e., organometallics)
Scaling microreaction technology / smart dimensioning
Session 2:
High-Temperature/pressure Flow Chemistry
Process intensification, flow chemistry in high-T/p process windows (Novel Process Windows), translating batch microwave protocols to flow
Multiphase Flow Chemistry – Part A
Multiphase flow regimes (slug flow etc.)
Liquid-Liquid phase reactions (phase-transfer catalysis)
Solid-liquid phase reactions (slurry handling, packed-bed reactors)
Flow mechanochemistry / reactive extrusion
Multiphase Flow Chemistry – Part B
Gas-liquid phase reactions (tube-in-tube, slug flow regime)
Gas-liquid-solid phase reactions/catalytic hydrogenation (packed-bed reactors, catalytic static mixers)
Session 3:
Chemical Generators – Hazardous Chemistries
On-site, on-demand generation of hazardous reagents/intermediates
Fluorinations using gaseous F2, SF4, etc.
Diazomethane in flow
Session 4:
Self-driving Labs, Automation and the Future of Continuous Processing
Data-rich experimentation using PAT, robotics and automation, slug-flow platforms for library synthesis and self-optimization (ML/AI)
Fully integrated modular flow systems
Session 5:
Meet the Experts at CCFLOW / Final Q&A session
Q&A Session with members of the CCFLOW Lab with a focus on technical/equipment issues
Benefits of Attending
- Learn what is flow chemistry and why go flow
- How to convert an existing lab reaction into a scalable flow process
- Research the choice of flow reactors available and when the choice of reactor is likely to be important
- Practical tips associated with handling, safety and scale up of flow reactions
Who should attend
- Industrial chemists
- Chemical engineers in process chemists in chemical development and scale-up
What's Included
The course fee includes:
- Link to watch all four live sessions
- Electronic version of the course manual*
- Course certificate
For this on line course, there will be no recordings available and *the e reader manual is NOT printable or downloadable (due to copyright). If you prefer a hard copy of the manual you will have the opportunity of purchasing a professionally printed hard copy during the booking process.
Other Information
Course Certificate
Upon completion of the course, participants can request a Certificate of Attendance.
Special Offers
1st delegate fee = Full price
2nd delegate fee = 5% off
3rd delegate fee = 10% off
4 or more delegate fees = 15% off
For more information on offers, do give us a call on +44 (0) 1892 956 222
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