Chemical Development & Scale-Up in the Fine Chemical & Pharmaceutical Industries
Principles and Practice
Event overview
Chemical process development is generally not taught as part of degree courses in higher education; the conversion of a synthetic route used for making milligram or gram quantities of a chemical into a process for manufacturing multi-kilogram and tonne quantities is typically learnt “on the job” by chemists in industry.
For many years, little chemical development work was published in the literature, until the establishment of the Organic Process R & D journal by Dr Trevor Laird (Founder of Scientific Update). Even now, “tricks of the trade” are handed down within individual company organisations, and it can be difficult to gain an awareness of what is involved in chemical development, and of the skills and techniques required to efficiently scale up chemical processes.
This three-day course, written and presented by highly experienced process chemists from the pharmaceutical and fine chemical industry, provides a comprehensive foundational overview of this fascinating and important element of the chemical industry. A logical investigative approach to all aspects of chemical development is described, with an abundance of case studies from literature, conferences and private communications. The multi-disciplinary nature of chemical development is emphasised, from the initial interaction with laboratory research scientists to the vital partnership with chemical engineers in the pilot plant and in the production environment. The lectures are interspersed with interactive problem sessions, enabling participants to share in the problem solving and troubleshooting typically experienced during chemical development.
Course Outline
The course comprises 15 lectures, delivered over three interactive days. Each lecture will be followed by dedicated time for Q&A, idea sharing, and problem-solving to foster a collaborative learning environment. The main topics include:
- Introduction
- Synthetic Route Design
- Synthetic Route Selection
- Safety Testing
- Heat Transfer and Thermal Runaway
- Process Understanding
- Process Optimization
- Statistical Methods of Optimization
- Planning for Scale-Up
- Mixing and Mass Transfer
- Solvent Selection
- Work-Up
- Crystallization and Solid Form
- Control
- Emerging Technologies
- Interactive Workshops
Benefits of Attending
- A logical investigative approach to chemical development and optimisation.
- An insight into the factors involved in development and scale-up.
- An appreciation of chemical engineering concepts, particularly mixing, heat transfer and process control.
- A preliminary knowledge of statistical methods of optimisation.
- Improved ability to decide which parts of the chemical process to examine in detail
- Ideas for efficient resource allocation
- Improved troubleshooting and problem solving ability
Who Should Attend
- Young Chemists who have just started work in industry as development chemists
- Organic Chemists/Medicinal Chemists in Research and Development who would like to gain an appreciation of development and scale up and who are perhaps contemplating moving into chemical development.
- Development and Production Chemists in industry who would like to improve their efficiency and gain an insight into alternative approaches to chemical development.
- Chemical Engineers who wish to understand a chemist’s approach to chemical development of batch processes. (Engineers would, however, need a good grounding in organic chemistry)
- Students who are about to enter the industry and can obtain company sponsorship.
- Experienced Chemists looking to refresh and/or augment their knowledge of chemical development
- Analytical Chemists who wish to gain a broader appreciation of process chemistry
- Managers who might benefit from a comprehensive and up to date overview of chemical development
Other Information
What's Included
Each course includes:
- A comprehensive printed manual
- Refreshment breaks & lunch daily
- Dinner on the first evening*
- Course Certificate
Please refer to the course brochure for detailed timings.
*Not all courses include a dinner, please refer to the course brochures for detailed information on what’s included.
Course Certificate
Upon completion of the course, participants will receive a Certificate of Attendance from the tutor. If an electronic version is required, please contact [email protected]
Accommodation
Depending on the venue, either we will secure a limited number of bedrooms at a fixed rate or provide a list of recommended hotels nearby.
Further information will be provided upon booking. All room reservations must be made directly with your chosen hotel.
Special Offer
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1st delegate: Standard rate
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2nd delegate: 5% discount
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3–6 delegates: 10% discount
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More than 6 delegates: Contact our Events Team for a customised group rate or to discuss an In-House course: [email protected]
Brochure
View Summary
Venue info
F-06200
Nice
France
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