Chemical and Process Safety for Development Chemists
Event overview
This course on chemical and process safety is designed for development chemists who are active in the field of chemical process scale-up, offering essential knowledge to ensure safety in chemical research and industrial processes. The course covers the fundamental principles of chemical safety hazard identification, testing, and risk assessment, focusing on the challenges faced by chemist’s working in process development. Participants will learn about the properties of hazardous chemicals and safe handling and storage procedures, how to find relevant safety data and how to assess specific reactivity hazards of chemicals with a strong emphasis on heat release, gas release and thermal stability.
Key topics include chemical reactivity hazards, thermal runaway reactions, and the principles of process safety management. Special attention is given to scale up from lab to pilot plant, highlighting the potential hazards and safety measures required at each stage. The course will help participants understand how to anticipate and prevent incidents and accidents and develop safer processes.
Through detailed case studies, attendees will develop a robust understanding of how to implement safety protocols in their work environment, minimising risk to personnel equipment and the environment. By the end of the course, attendees will have an appreciation of the principles important for safe scale-up and be equipped with the necessary tools to contribute to a culture of safety in their organisations.
This online course will take place over four afternoon sessions, see below times and dates.
Timings for each session
EST: 1.00pm-4.00pm | PST: 10.00am-1.00pm | GMT: 6.00pm-9.00pm | CET: 7.00pm-10.00pm
Monday 17th February 2025
Tuesday 18th February 2025
Monday 24th February 2025
Tuesday 25th February 2025
Course Outline
Introduction
- Large scale batch equipment
Retrieving safety information
- Where to find safety information
- Pitfalls of SDS data
Chemical choices
- Choice of solvent
- Choice of reagent : the usual susptects
Process safety at larger scale
- Runaway scenario
- Criticality classes
Heat evolution
- Rules of thumb
- Reaction calorimetry
- Heat transfer coefficients
- Safe scale-up of heat removal
- Safety at reflux
- Calculation of dosing times
Gas evolution
- Rules of thumb
- Measuring gas evolution in the lab
- Safe scale-up of reactions with gas evolution
Study of the decomposition reaction
- Screening methods
- Adiabatic calorimetry
- Autocatalysis
- Determination of TMRad,24h
- Kinetic modelling
Upstream and downstream
- Safety aspects of storage of unstable chemicals
- Safety incidents with waste streams
Flow chemistry
- Safer processing in flow
- Safety evaluation of flow processing
Requirements for safety studies
- Intended process vs upset conditions
- Interaction matrix
- Chemical compatibility
Who Should Attend
- Lab chemists working in process development
- Chemical engineers working in chemical production and tech transfer
- R&D managers in chemical development
What the delegates will gain
- Understand the effect of heat and gas evolution on large scale synthesis
- Understand how preliminary lab data can give insight in possible safety issues at scale
- Understand how chemical reactivity can influence upstream and downstream issues in storage and waste streams
- Understand how chemistry involved can influence operational issues like heat transfer, gas removal and reflux
- Understand which data is needed for safe scale-up of batch processes
What's included
The course fee includes:
- Link to watch all four live sessions
- Electronic version of the course manual*
- Course certificate (upon completion)
For this online course, there will be no recordings available and *the e reader manual is NOT printable or downloadable (due to copyright). If you prefer a hard copy of the manual you will have the opportunity of purchasing a professionally printed hard copy during the booking process.
Other Information
Discounts
1st delegate = Full price
2nd delegate fee = 5% off
3rd delegate fee = 10% off
4 or more delegate fees = 15% off
For more information on discounts do give us a call on +44 1892 956 222
Certificate
Upon completion of the course, participants can request a Certificate of Attendance.
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