Nitrous oxide- discovered by Joseph Priestley in 1772 and known affectionately as “laughing gas” – is now a class C drug in the UK under the misuse of drugs act 1971. Possession will be illegal by the end of 2023. If, However, you can get hold of some (or have some to get rid of)

Tert-butyl phenols are important commodity chemicals, with annual production exceeding 120,000 t per annum. They have multiple industrial applications including agrochemicals, antioxidants- in particular 2,6-di-tert-butyl-4- methylphenol (BHT, Figure 1), foods, flavours and fragrances and pharmaceuticals.1 BHT in particular, used as an antioxidant in polymers and oils and prepared by reaction of p-cresol with isobutylene in

Phenols and anilines are two of the most important building blocks in industrial chemical manufacturing. Any process capable of converting one into the other is going to generate a lot of interest, and a paper by Shi and co-workers does just that.1 Direct conversion of an aniline to a phenol is a relatively straightforward transformation

The direct halogenation of phenols using electrophilic halogenating reagents such as NBS are frequently used to prepare halogenated phenols. The problem with this method is that selectivity can often be low- the ortho– isomer is usually the minor component in a statistical mixture due to steric and electronic effects, and over reaction to give polyhalogenated