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Young Chemist Award Winners 2019

We were absolutely delighted to present the awards to our 11 Winners of our ‘Young Chemist Award’ at our ‘6th Winter Process Chemistry Conference’ in Birmingham today. They have all presented their work at the conference and it has been fantastic to hear from them all. Thanks to our judges – Ian Lennon at #chiralquest,

What is the simplest marketed therapeutic?

Lithium (Li, Element 3) Lithium, first member of the group 1 alkali metals, was discovered in 1817 by Johan August Arfwedson. It’s been around since the dawn of (astronomical) time- both stable isotopes, Li6 and Li7, being among a small handful of elements created in the Big Bang.1Terrestrially its highly abundant in seawater (up to

Syntactic fantastic:

A highly diastereoselective chloride-ion driven dynamic kinetic resolution of a phosphinate ester- a key step in the synthesis of Fosdevirine Fosdevirine (or GSK2248761A, top figure) is a non-nucleoside reverse transcriptase inhibitor, originally discovered by Idenix pharmaceuticals for the treatment of HIV infection. The structure is somewhat unusual in that it contains a phosphorus stereogenic centre-

Phase Transfer Catalysis Tips and Abstracts from PTC Organics, Inc

A patent just issued last month to Sachem, one of the most veteran manufacturers of high purity quaternary ammonium phase-transfer catalysts, that describes how to inhibit color formation of quat hydroxides in non-aqueous solvents (glycols). Sachem has been a leader in the commercial supply of quat hydroxides, especially those used in the manufacture of semiconductors.

OPRD US 2018 Conference

We had a fantastic turn out for our #OPRDUS18 Conference in Clearwater, Florida last month. It was great to see our speakers, exhibitors and attendees and the feedback we received was excellent. Thank you for coming along! Our Technical Director Dr Will Watson opened the conference and we invited Dr Paul Murray and Dr André de

Sustainability and Analysis

Considering the environmental footprint of a typical pharmaceutical / agrochemical process, 60-80% arises from the use of solvents.  Good solvent selection and use – can be the biggest positive hit on improving the sustainability of a process. The timely identification of an optimum chemical route can save you time and money.  An efficient route, selected

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