Yesterday I glanced through the list of drugs approved by the FDA in Q2 2023. One in particular, Miebo,1 -developed by Bausch and Lomb- made me sit up and stare. The compound is a partially fluorinated alkane (1-(Perfluorohexyl)octane, Figure 1) and is administered directly into the eye as a neat, anhydrous liquid to treat dry
Tag: Fluorination
In the spring of 1940, John Archibald Wheeler, eminent theoretical physicist, called up his then PhD student, Richard Feynman (generally regarded as the most famous modern-age physicist) and said “Feynman- perhaps there’s only one electron in the Universe” a single entity moving backwards and forwards in time. If true it would be one hard working
In June of 1886 (26th to be precise) the French chemist Henri Mossian passed an electric current through a solution of KHF2 in anhydrous HF and became the first person to generate fluorine. Rather him than me. But he did, quite rightly, win a Nobel prize for his efforts in 1905. Since then, methods to