We recently had the pleasure of speaking with Iwona Kaluzna, Sales and Marketing Director at InnoSyn to learn about the key challenges and most exciting research areas in biocatalysis. Read the blog article by Laura Elizabeth Lansdowne, Senior Science Writer & Editor, Technology Networks: Link to article: Advances in Industrial Biocatalysis Iwona is presenting at
Nature has had many generations to optimise its catalytic processes. As a result they are both extremely efficient and exquisitely selective. Biocatalysis is now very much a mainstay of industrial organic synthesis, particularly with the advent of protein engineering and directed evolution enabling the preparation of robust enzymes fine-tuned to a particular substrate. The importance
Francis Arnold and her group have published a series of papers using modified Cytochrome P450 enzymes to cyclopropanate olefins with diazo esters1. More recently they have used a related system to create chiral carbon-silicon bonds2. P.S. Coelho, E.M. Brustad, A. Kannan, and F.H. Arnold et al, Science, 2013, 339, 307-310; Z.J. Wang, H. Ranata, N.E.