Following a communication from a chemist at Merck / MSD I can now tell you about 2 more cocrystal APIs on the market – Lexapro (escitalopram oxalate) and Steglatro (ertugliflozin pyroglutamic acid cocrystal. Lexapro is actually a cocrystal of the salt escitalopram oxalate with oxalic acid, similar in some ways to the Praziquantel intermediate naproxen
Tag: cocrystal
There are now 3 cocrystal API’s (Entresto, Suglat, and Depakote) on the market meaning that this area is no longer just an academic curiosity. Entresto is a cocrystal formed from the sodium salts of sacubitril and valsartan, but I do not know whether that is affected by the current furore over N-nitrosoamine impurities found in