Partner Listings

Allotrope Scientific Ltd

At core, Allotrope Scientific Ltd provides scientific and technical expertise in developing a robust and sustainable process to take your molecule from lab to market.

From phase appropriate route scouting, solid form selection to route development, process characterisation, particle engineering and validation; we guide all the way from preclinical to commercial supply, including authoring of your drug substance regulatory filings. If necessary, we are also resourceful in helping you find the right partner for development and manufacture, and sourcing of reliable suppliers of key starting materials.

We are passionate about organic chemistry and enjoy the art of organic synthesis. Recently, we have expanded into providing custom synthesis of 14C radiolabelled intermediates and APIs. We enjoy problem solving and developing an understanding of what happens in a reaction. This helps us in supporting you with syntheses and supply of challenging impurities.

Arcinova

Arcinova is a UK-based Contract Development and Manufacturing Organisation (CDMO) serving the global pharmaceutical and biotechnology communities.

From our single 15,000m2 facility, which has benefited from more than 36 years of investment as a key R&D centre for Sanofi and Covance, we can support our clients’ needs with a wide range of services such as: drug substance development and manufacturing (including GMP, [¹⁴C]-labelled products and high potents), material sciences, formulation and drug product manufacturing.

We can manufacture both drug substance and drug products from grams to multi-kilo scale.

We also offer supporting analytical services including, investigations and development of QC specifications, microbiological and stability testing as well as a regulatory CMC dossier writing service.

Finally, our experienced bioanalytical team can develop, validate and implement bioanalytical assays for small and large molecule drugs, generics and biomarkers to support both clinical and non-clinical studies.

Boegringer Ingelheim

Boehringer Ingelheim is working on breakthrough therapies that transform lives, today and for generations to come. As a leading research-driven biopharmaceutical company, the company creates value through innovation in areas of high unmet medical need. Founded in 1885 and family-owned ever since, Boehringer Ingelheim takes a long-term perspective. More than 52,000 employees serve over 130 markets in the three business areas, Human Pharma, Animal Health, and Biopharmaceutical Contract Manufacturing. Learn more at www.boehringer-ingelheim.com

Codexis

Our proprietary CodeEvolver® protein engineering technology platform enables the rapid development of highly optimized proteins, custom-designed for our clients’ specific therapeutic or process-relevant applications.

Digital Specialty Chemicals

DSC’s product line includes phosphine ligands (including Buchwalds) for homogeneous catalysis, phosphorylating reagents and challenging organometallics, available from kilogram to metric ton quantities. DSC offers custom manufacturing services, with focus on air, moisture and heat sensitives.  WE MAKE CHEMISTRY MATTER.

FCG Chemical

FCG Chemical works with clients to develop flow processes using our microwave reactor test platform.  By using our flexible suite of reactors, we offer a rapid pathway to identifying the economic advantages of microwave driven, flow chemistry.  Our reactor technology is flexible, modular and can be customized to match production needs.

Fraunhofer ICT-IMM

The core competencies in continuous chemical engineering include development and simulation based design of micro reactors, realization of plants for lab, pilot and production scale and process development based on microreactors and flow chemistry.

Huber

With service and store facilities in Derbyshire and Dublin, Huber UK and Ireland are ideally situated to support your application form small to large scale chemistry.  Our products ensure precise temperature control in laboratories, pilot plants and production processes throughout the whole world – from -125 °C to +425 °C.  Besides dynamic temperature control systems we develop and produce chillers as well as classic heating and cooling circulators. For many applications we supply custom-tailored solutions, which we develop in cooperation with our customers.

Innosyn

Innosyn has an unbiased approach to “invent, improve and/or implement” the best process for your challenging chemistry.

JULABO USA, Inc.

The NEW Presto units cover every temperature application from- 92°C to +250°C from bench top to pilot plant scale.

Keit Spectrometers

Keit is a technology-driven company launched from the European space programme with applications in the global marketplace. Keit offers real-time reaction analysis of liquids in manufacturing processes of chemicals, oil & gas, biofuels, and food & beverages with a solid-state instrument.  The IRmadillo FTIR spectrometer provides in-line process monitoring in challenging environments where standard instruments fail.

Jim Rutherford from Keit presented a paper at ‘4th Hazardous Chemistry Conference for Streamlined Large Scale Synthesis‘ in Antwerp, November 28th & 29th 2017. You can view his presentation using the link below:

Keit Presentation

Key Organics Ltd

Key Organics has over 30 years’ proven expertise and competence, supplying to a global client base our high quality ‘BIONET’-branded catalogue products (>200,000) for early-stage drug discovery research.

Product lines include; Fragments, Biochemicals, Screening Compounds, Research Intermediates, Agrimediates^TM and Core Scaffolds.

We also have extensive experience in the delivery of bespoke Chemistry Services, e.g. Custom & Contract Synthesis and Collaborative R&D. We have an enviable reputation in FTE services provision from our highly-qualified and skilled team of chemists.

Operating out of our own premises in Cornwall, we cater primarily for the pharmaceutical, biotechnology and agro/petrochemical industries.

Lhasa Limited

Lhasa’s software includes Mirabilis, an expert knowledge-based tool for calculating the purge factors of potentially mutagenic impurities, as well as Derek and Sarah Nexus, which can help with ICH M7 submission.

Magritek

Founded in 2004, Magritek is the global leader in manufacturing cryogen-free benchtop Nuclear Magnetic Resonance (NMR) spectrometers for the analytical instrument market. Magritek’s revolutionary 80 MHz, 60 MHz and 43 MHz Spinsolve family of benchtop NMR models offer the highest sensitivity and resolution available in the market.  These portable systems are robust and easy to use, allowing modern NMR methods to be performed on the chemistry lab bench or inside the fume hood next to a reactor. Magritek has offices in Germany, USA, and New Zealand, as well as a worldwide network of partners, to help support its customers. Learn more at www.magritek.com.

 

Patheon

With approximately 8,700 employees worldwide, Patheon provides a comprehensive, integrated and highly customizable set of solutions to help clients of all sizes satisfy complex development and manufacturing needs at any stage of the pharmaceutical development cycle. A Healthier World. Delivered.

Powder Systems Ltd

Powder Systems Ltd (PSL) is an award-winning global manufacturer of innovative technologies and process services for the pharmaceutical, bio-pharmaceutical and chemical industries.

With a successful track record, built up over the last 30 years, PSL is widely recognised for its high level of quality and expertise in pharmaceutical and chemical processing. We provide a full range of filtration and drying process systems from small R&D up to larger commercial production scale, which can also be combined with our containment systems for advanced operator protection.

Our pioneering solutions enable pharmaceutical manufacturers to improve their processes and adopt the latest advances to produce their medicines in a safer, better and more cost-effective way. Our technology is used within the industry every day, from early development works with our GFD® range (filtration & drying of powders), to new-generation drugs with the MSR™ platform for complex microsphere based injectables.

Radleys

Changing the way you do chemistry.

Chemistry isn’t just something we do. It’s everything we are.

We’ve been manufacturing scientific glassware and laboratory instruments for over 50 years. Committed to innovation, all of our products are designed to give users the flexibility and freedom to conduct chemical research in the way they want.

Scale is no barrier – from research to development, benchtop to production, we create the tools needed for safer, cleaner, greener, more productive chemistry. With in-house research and development facilities, we focus on equipment for chemical synthesis and process development.

Sinocompound

Sinocompound is a global provider of advanced homogeneous catalysts and ligands and specialist services for a range of pharmaceutical and fine chemical applications. Our proven process is built around our next generation technologies, flexibility, and speed-of-response ensuring delivery at the scale required for your project. Our success is due to our dedication to listening to customers and developing bespoke solutions that help the industry overcome its challenges and customers accelerate their route to market.

SK Pharmteco

Profile

SK pharmteco specializes in the commercial and clinical production of APIs, Advanced Intermediates, Registered Starting Materials, Key Building Blocks and Viral Vectors. Our offerings include process R&D, analytical method development and stability, scale-up and optimization, validation and commercial production. Additionally, we offer extensive AAV and Lentiviral vector development and cGMP production capabilities.

Our global operations include 7 cGMP manufacturing and development facilities across the US, Korea, Ireland and France. We also operate a dedicated analytical services facility.

SK pharmteco is a leader in operational excellence and continuous improvement. Our highly skilled team delivers innovative solutions utilizing advanced technologies:
– Continuous Flow Processing
– Chromatography: SMB & Batch
– High Potency (Up to 4 m³ scale & down to 10 ng/m³
containment)
– Energetic Chemistry
– Controlled Substances (Sch II-V Manufacturing)
– Particle Engineering
– cGMP Manufacturing in Adherent & Suspension Systems for
Viral Vectors
– Analytical & Process Development for Viral Vectors

We have a strong record of environmental, health, and safety performance. All our plants have been successfully audited by global regulatory agencies including the FDA (US), EMA (Europe), PMDA (Japan), & MFDS (Korea).

Strong technology toolbox & ~1,000 m³ of global small-molecule capacity + 5k m² of large

Products & Services

– Continuous Flow Processing
– Chromatography: SMB & Batch
– High Potency (Up to 4 m³ scale & down to 10 ng/m³
containment)
– Energetic Chemistry
– Controlled Substances (Schedule II-V Manufacturing)
– Particle Engineering
– cGMP Manufacturing in Adherent & Suspension Systems for
Viral Vectors
– Analytical & Process Development for Viral Vectors

We provide PAI and full regulatory support.

Solvay

The use of such compounds has grown to become a key component for many blockbusters in the Pharma and Agrochemicals sector. Solvay’s product range covers well known CF3-derivatives like Trifluoroacetylchloride, Trifluoroacetic acid and Triflic acid and it’s derivatives as well as downstream products like 4-Ethoxy-1,1,1-trifluor-3-buten-2-on, some fluorinated Pyrazoles, Pyrimidinones and Pyridones and fluorinated Ionic liquids.

Stoli Chem

Design and develop scalable flow reactors to convert batch chemistry to flow.

Utilising over 15 years of experience in process design and catalysis, Stoli work closely with you to optimise production efficiency.

Our scalable multipurpose flow reactor offers a straight forward route to scale-up from lab to pilot to production scale. The modular design allows for changeable inserts to accommodate liquid-liquid, liquid-gas and solid-liquid reaction types.

Independent stirring and flow rate allow for efficient mixing even at long residence times.

Visit us to discuss how our technology can benefit your company and to organise a reactor trial.

Web:  https://stolicatalysts.com/
LinkedIn:  https://www.linkedin.com/company/stoli-catalysts/

Strem Chemicals UK Ltd

Strem Chemicals UK Ltd has had a presence in the UK and Ireland for over twenty five years. We distribute a wide range of high purity chemicals and specialty materials.

These include:

1. A range of metals, inorganics, organometallics and nanomaterials
2. We offer patent-free and proprietary catalysts and ligands for organic synthesis, often at kilo-scale, including many for asymmetric transformations
3. For the materials science/electronic community we include a wide range of MOCVD, CVD and ALD precursors & bubblers, metal-based nanomaterials (including PURE nanoparticles that are reactant and surfactant-free) quantum dots (including Graphene) and carbon nanomaterials (nanotubes, fibres, cones, CNT arrays, graphene), rare-earth and electronic grade chemicals for ultra-high purity needs and ionic liquids

Our licensed technologies come royalty-free for R&D purposes.

Our clients include academic, industrial and governmental research laboratories as well as commercial scale businesses in the pharmaceutical, microelectronic and chemical industries.

We are certified compliant to ISO 9001 and 14001.

Syrris

Syrris takes pride in designing, developing and selling easy to use automated products for chemists in areas such as the pharmaceutical industry, academia, CROs, petrochemical industry etc. Syrris have two major product types: batch reactor systems and flow reactor Systems.

Teledyne

Teledyne ISCO’s pumps are designed for reaction chemistry, focused on the delivery of pulseless and precise flow in order to ensure the highest yield. If you need precise, positive fluid metering for bench-scale R&D; batch or continuous processing, liquefied gases, or supercritical fluids, take a look at what ISCO Syringe Pumps have to offer. By adding in some of our accessories, you can control the temperature of the fluid or keep the fluids in suspension.

Our line of Flash and HPLC systems includes instruments and accessories for the purification of organic compounds in normal-phase and reversed-phase separations, and for bio-purification of proteins, peptides, and other biopolymers. The ACCQPrep HP 125 is one of our newer additions to our product offering. We also now offer the CombiFlash NextGen line which provides numerous models to choose from based on your budgetary and application needs in flash chromatography performance.

 

Thar Process

Vapourtec

Vapourtec develops, manufactures and markets cutting-edge flow chemistry systems for fine chemical discovery and process development. Customers for Vapourtec’s products include blue-chip companies and research institutes developing, pharmaceuticals, agrochemicals, fragrances, advanced materials and other fine chemicals.

Wilmington PharmaTech Company

Today, WPT is known as one of the best and fastest API supplier in US or even in the world.

Our capabilities include:

• cGMP Synthesis
• Stable Isotope Labeling
• Bulk Intermediate Production
• FTE/Time-Based Process and Analytical Research
• Salt and Polymorph Screening
• Genotoxic Impurities (GTI’s) and Trace Analysis
• Analytical GLP/GMP full Services
• ICH stabilities and sample storage
• Impurities ID, Preparation and qualification: Process impurities, stability impurities, and metabolites
• R&D areas: Chiral separation, Continuous Flow Reactions, Nucleotides, Oligonucleotides

Current expansions: US Based pilot production plant, HPAPI suites, and Bioanalysis

WuXi AppTec

WuXi AppTec provides a broad portfolio of R&D and manufacturing services that enable companies in the pharmaceutical, biotech and medical device industries worldwide to advance discoveries and deliver groundbreaking treatments to patients. As an innovation-driven and customer-focused company, WuXi AppTec helps our partners improve the productivity of advancing healthcare products through cost-effective and efficient solutions.

Zaiput Flow Technologies

Zaiput Flow Technologies brings to market unique liquid-liquid and gas-liquid technology designed for flow and batch chemistry applications. We offer a scalable separation solution from bench to production. Our devices offer continuous operation, can readily separate emulsions and liquid with identical density. The modularity of the devices allows for both single and multistage operation in a variety of possible configurations

ZEON CORPORATION

CPME contributes to Green Chemistry and Process Innovation because of its unique properties including a high hydrophobicity, low peroxide formation and good stability to acids.