Process Chemist

Sai Life Sciences Limited
Alderley Park, Macclesfield, Cheshire, SK10 4TG
permanent
gbp30000 - gbp50000

Job description

CLOSING DATE 29th Feb 2020

Sai Life Sciences is a Contract Research & Development and Manufacturing Organisation working with 7 of the top 10 pharma companies globally, as well as many leading niche biotech's. The company works with its clients to accelerate the discovery, development and manufacture of complex small molecules for a healthier tomorrow. With more than 2000 staff and ambitious growth plans, their vision is to support their global innovator partners to bring 25 new medicines to life by 2025.

 

Following a significant investment in a state of the art laboratory at the Alderley Park Biotech & Life Science Cluster, Sai Life Sciences is now creating a centre of excellence (COE) for process chemistry and analytical development. The COE will identify, develop and optimise synthetic routes to API, supporting both early and late development. It will also manufacture non-GMP kg quantities of intermediates and APIs in its bespoke Scale-up laboratory facility. The developed processes may then be transferred to Sai Life Sciences manufacturing sites across India.

This is an opportunity to shape the development of a world leading laboratory and work closely with some of the most innovative biotech and pharma companies on their most important programmes.

The Role:

Sai Life Sciences are looking for a number of Scientists who are seeking a new challenge to support the initiation of our new Process Development team.

 

The successful candidate will either have a strong technical grounding in Organic Chemistry with 1-5 years' experience in a relevant industry or will be someone who has recently completed (or who will complete during 2020) a BSc, MSc, PhD or Post-doctoral research project with a specialism in Organic Synthesis or Process Chemistry.


Demonstrated expertise in early, mid or late-phase route and process development for the manufacture of APIs, intermediates and raw materials, and/or experience with quality by design, technology transfer and commercial production would also be advantageous.

 

The candidate is expected to conduct practical, laboratory based chemistry projects to develop routes and processes and then scale-up to manufacture.

 

Essential Requirements

  • Higher or Bachelor Degree in Chemistry or related scientific discipline with relevant experience in a chemistry laboratory environment.
  • In-depth, hands-on expertise and up-to-date knowledge of a wide range of organic chemistry transformations.
  • Strong scientific track record

 

Key Roles and Responsibilities

  • Design and conduct laboratory experimentation to deliver customer projects.
  • Deliver new routes and processes for early-phase APIs and intermediates to enable scale-up to 20L at Alderley
  • Deliver optimised processes for mid and late-phase APIs and intermediates to enable scale-up to pilot and production facilities in India.
  • Working within multi-functional project teams operating to tight deadlines
  • Learning agility in the utilisation of new technologies and approaches to support chemistry projects
  • Ability to solve complex scientific problems

 

The successful candidates will have a flexible approach to their work and demonstrate the following attributes:

  • Excellent communication; both verbal and written
  • A team player
  • Conscientious with a can-do attitude with good attention to detail

 

The Offer:

  • A competitive Salary and Benefits package
  • Work in a state of the art laboratory on one the country's leading Biotech & Life Science Parks
  • Access to great facilities including an on-site gym.