Archived: Organic Process Research and Development On Line

The Leading Process Chemistry Conference!

Time: 2.00pm (UK); 3.00pm (Central Europe); 10.00 am (EST); 6.00 am (PST) each day - 5.30pm

Location: Online Platform

Due to the ongoing Pandemic, we have decided to deliver our Flagship Conference “Organic Process Research and Development” VIRTUALLY

This has been a difficult decision to take and we are very disappointed that we will not be bringing the industry together in person this year. However, we are confident we can still provide a place for the industry to gather, hear important industry case studies and network with peers. It also opens the doors to industry representatives who may have been unable to travel to the event in the past. So we are excited to share with you our plans for this online event, with 10 industrial case studies, a virtual exhibition, and networking opportunities via our hosted discussion groups on industry relevant topics. We hope you will be able to join us in December.


The efficient conversion of a chemical process into a process for manufacture on tonnage scale has always been of importance in the chemical and pharmaceutical industries. However, in the current economic and regulatory climate, it has become increasingly vital and challenging to do so efficiently.

At Organic Process Research & Development Conference, you will hear detailed presentations and case studies from top international chemists. Our hand-picked programme of speakers has been put together specifically for an industrial audience. They will discuss the latest issues relating to synthetic route design, development and optimisation in the pharmaceutical, fine chemical and allied fields.

Unlike other conferences, practically all our speakers are experts from industry, which means the ideas and information you take home will be directly applicable to your own work.

Our virtual conference program will be held over three consecutive days with 2 sessions and up to 4 speakers on each day. After you have registered you will be provided with a personal link to join all conference sessions.

Via the ‘GotoWebinar’ Platform, there will be the chance to listen to the talks, view the speakers slides and ask questions after each session. The Virtual conference will be held during the following times (based on UK timing) as we hope this will allow most people to join from around the world.  This event will NOT BE RECORDED – we apologise to customers in Asia or Australia who might be unable to join.

Wednesday December 9th 2020 |  2.00 – 5.40 pm (UK)
Thursday December 10th 2020 | 2.00 – 5.45 pm (UK)
Friday December 11th 2020 | 2.00 – 5.45 pm (UK)

There will be a VIRTUAL Exhibition too so you will be able to have access to suppliers of  equipment, technology and services and request 1-2-1 meetings. Via Zoom, you will also have the opportunity to meet and network with some of our sponsors, who will be hosting specific topics in Hosted Discussion Groups – provisional details  are below.

Please contact us if you are interested in Exhibiting or Sponsoring this event:  [email protected]

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  • Process Research & Development Chemists
  • Chemical Engineers in Industry
  • Heads of Departments & Team Leaders


  • Continuing Professional Development (CPD ) keeps you up to date on current and emerging developments.
  • Learn from a wide range of industrial case studies given by hand-picked industrial speakers.
  • Take home relevant ideas and information that are directly applicable to your own work
  • Save time. Our intensive, commercial-free programme means less time away from work.
  • Network with the key people in the industry in dedicated break out rooms

Hosted Discussion Sessions

Via Zoom, you will be able to choose from a selection of Hosted Discussion Sessions on industry related topics. These sessions will be provided by key stakeholders within the industry. Our hosts will provide product demonstrations, virtual lab tours, industry updates and panel discussions.

SESSION  1 |  |Wednesday 9th December,  5.00 – 5.45 pm (GMT)  Choose one from the following:

Room 1 |  Johnson Matthey

Catalysis for Fine Chemicals: Opportunities for Optimized Processes

This will be an interactive session where we will be discussing four topics of homogeneous catalysis with focus on how to maximize efficiency and value.

  • Pd-catalysed coupling: comparing generations of catalysts for efficiency and catalyst cost contribution;
  • Ru-catalysed ester hydrogenation: disruptive technology vs traditional methods (e.g. hydrides);
  • Ru-catalysed transfer hydrogenation: value proposition of two generations of catalysts and the importance of process optimization (and how to do it);
  • Rh- catalyzed hydrogenation: where the technology is going and considerations on the economics of using precious transition metals.

Room 2 |  Technobis Crystallization Systems

Solvent Selection in Pharmaceutical Crystallization Process Development

Choosing an appropriate solvent is the cornerstone of good crystallization development. The solvent system from which an active pharmaceutical ingredient (API) is crystallized, influences solubility, growth and nucleation kinetics, impurity purging, polymorph control, solvation propensity and crystal morphology. Despite the importance of this choice, in early phase development, solvents are typically chosen based on chemical intuition with only the impact of product yield considered. This can lead to insufficient purity, unfavourable particle size and serious processability issues in later phases of both drug substance and drug product development.

Making use of predictive modelling and smart experimentation, a platform may be developed to enable optimal solvent selection across eight criteria: yield, productivity, antisolvent efficiency, solvation and oiling propensity, impurity rejection, seedability and safety and environmental choices.  This discussion will consider these issues.

Room 3 |  Phosphonics

Optimising Scavenging Processes for more Sustainable and Cost Effective Chemical Processes

Catalysis is ubiquitous in the chemical industry and is a key pillar of green chemistry. We will discuss with the attendees their use of catalysis, showing how scavenging can be a more cost effective solution than most people imagine. We will share our approach to optimising cost effective scavenging processes and share case studies on the removal of metal impurities to meet the ICH guidelines as well as the recovery of value from waste streams for more cost effective and sustainable catalytic processes. 

SESSION  2  |  Thursday 10th December,  5.00 – 5.45 pm (BST)  Choose one from the following:

Room 4 |  Scale Up Systems

Kinetics Workshop – Converting Experimental Data to Process Knowledge

Mechanistic reaction models provide the basis for deep process understanding, and thus the platform to reduce development times of optimized, robust reaction steps ready for scale-up in the pharmaceutical, and agrochemical, and fine and speciality chemicals industries.

Join this session with Dr Charles Gordon who will outline his experiences in using kinetic models for API process development and the steps that process and synthetic chemists can take to bring benefits to their own projects by following this approach.

Room 5 | Merck

Supporting Chemical Synthesis and Applications from Bench to Bulk Scale

Polymers, reagents, solvents, and catalysts are likely to undergo rapid demand increases from milligrams/grams to kilograms/tons due to their broad applicability as production materials within the chemical and pharmaceutical industry. “Bench2bulk” chemical products maintain high quality, competitive price, on-time delivery, full documentation, and custom options regardless of the requirement scale.

Dr. John Nguyen and Dr. Amitkumar Pandya will highlight prominent uses/applications, discuss bulk business challenges, and share success stories for bench2bulk polymers, ligands, and metal catalysts.

Room 6  |  Umicore

Sustainable Precious Metal Catalysis: Contradiction or Not?

 As interest in abundant metal catalysis continues to grow, statements in peer-reviewed articles pointing out the rarity of platinum-group metals (PGMs) are common. Is that a reason to question their sustainability? The impact of shortening a synthetic sequence or eliminating a solvent-intensive purification by using a highly active and selective precious metal catalyst often far outweighs its cost, and outlines that sustainability should never be considered from a single dimension. Furthermore, there is potential to recover and re-use the precious metal through a closed-loop process that is often underutilized.

This discussion will address the following topics:

  • An overview of the role of catalysis in green chemistry
  • Benefits and trade-offs of using precious metal and non-precious metal catalysts
  • Getting the most out of a closed-loop recovery solution


If you have a specialist topic and would like to host one of these session, please contact Claire Francis


Thank you to our 5 Star sponsors

Thank you to our 4 Star sponsors:





Thank you to our 3 Star sponsors:





I really enjoyed the conference.  I thought that the range of talks was fantastic and the site trip was really interesting.  It was great hearing speakers from other industries that use organic chemistry (fragrances and flavours and using organic chemistry for LCDs).

Bristol-Myers Squibb

The quality of the talks was outstanding. I appreciated the fact that several facets of process research were covered in this conference. Truly learned a lot!

Eli Lilly

I thought it was an especially strong line-up this year and had a great time during my stay. As always Scientific Update put together a great line-up at great venues


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