Last weekend, I attended a celebration party for my PhD supervisor Professor Nicholas J. Turner on the occasion of him being elected as a Fellow of the Royal Society. This is a prestigious accolade only bestowed upon a few very worthy scientists including 85 Nobel laureates. Nick was elected as FRS in 2020 but due
Month: May 2022
We are very pleased to introduce Dr Jen Crawford from GSK. Jen will be talking about ‘Implementing Statistical Modelling Tools into Early Phase Process Development Workflows’ at our ‘Organic Process Research and Development Conference’ in New Orleans on 22-24 June. This presentation will describe high throughput experiments (HTE) which provide an opportunity to traverse large
The count down has begun and we only have one month to go now until we come to New Orleans for our ‘47th Organic Process R&D Conference’ on 22-24 June. We are so excited about holding this face to face event in such a vibrant brilliant location! The 3 day meeting will include 16 presentations
Scientific Update to Welcome New Technical Associate for North America & Asia Pacific – Dr Ben Littler Scientific Update is delighted to announce the appointment of Dr Ben Littler, formerly Executive Director Process Chemistry for Vertex Pharmaceuticals. Ben will join the team at Scientific Update in August 2022 as Technical Associate, North America & Asia
Phenols and anilines are two of the most important building blocks in industrial chemical manufacturing. Any process capable of converting one into the other is going to generate a lot of interest, and a paper by Shi and co-workers does just that.1 Direct conversion of an aniline to a phenol is a relatively straightforward transformation
Process chemists at Genentech recently published their work on development of a kilo-scale synthesis of JAK-1 inhibitor- GDC-4379 (Figure 1).1The central heterocyclic core of the molecule consists of a 4-aminopyrazole moiety (elaborated as the pyrazolopyrimidene amide- presumably the inhibitor hinge binding fragment in the kinase active site) with an additional aryl substituent at C-3 and
