In March 1989, two chemists, Stanley Pons and Martin Fleishmann, stunned the world by claiming that an electrical current from a palladium electrode immersed in a test tube of water had resulted in nuclear ‘cold fusion’ at room temperature.1 For many years, attempts to understand and reproduce this seemingly impossible result- with sketchy information from

Back in August I posted a scheme for the synthesis of a late-stage intermediate towards PF-06826647, a compound identified by Pfizer as a potent and selective tyrosine kinase 2 (TYK-2) inhibitor. I asked if you could identify reagents or intermediates A, B and D. Below are the answers! You can read more here in the full